Mae is known for creating, co-writing, and starring in Feel Good, a scripted, semi-autobiographical comedy-drama series. Co-starring Lisa Kudrow and Charlotte Ritchie, the series launched globally on Netflix and Channel 4 in the UK to widespread praise and a perfect 100% “Certified Fresh” score on Rotten Tomatoes. Mae’s performance earned them an RTS "Breakthrough Award" and Bafta TV award nomination as well as "Best Comedy Writer" again at RTS. Feel Good also won The Writers Guild of Great Britain Award for "Best Situation Comedy", the Edinburgh TV award for “Best Comedy,” the NME Award for "Best TV Series," the “Best Comedy Drama series” at the C21 award and "Best Scripted Representation of LGBQT+" at the Mipcom Diversify Awards.

Mae's stand-up show, Dope, focused on addiction and was nominated for "Best Comedy Show" at the prestigious Edinburgh Comedy Awards while earning four and five-star national reviews in the UK. The show has since been turned into a stand-up special for Netflix as part of their first global stand-up series, Comedians of the World.

Mae Martin's Guide To… series about sexuality and addiction was both BBC Audio Drama Award nominated and is available to listen to on BBC Sounds. Mae is also the author of Young Adult focused Can Everyone Please Calm Down?: A Guide to 21st Century Sexuality.